Starch-based orodispersible film for diclofenac release
نویسندگان
چکیده
The form of drug administration affects the success treatment, since it can influence adherence patient to therapy. use orodispersible films has emerged as a way overcome some drawbacks conventional methods delivery, especially for patients experiencing difficulty in swallowing. These are prepared using matrix that incorporates and contains other substances confer properties system. present work describes thermoplastic starch carrier model diclofenac, including film preparation testing its potential. Preparation employed microwave oven gelatinize plasticize corn starch, with incorporation drug, followed by solvent-casting. samples were characterized mechanical tests, analyses water uptake content, Fourier transform infrared spectroscopy. results indicated presented promising an alternative system oral administration, good distribution matrix. material displayed satisfactory properties, which crucial this type material, due need handling before use.
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2023
ISSN: ['2175-9790', '1984-8250']
DOI: https://doi.org/10.1590/s2175-97902023e211019